Association of buffalo sperm protein kinase with sperm chromatin
نویسندگان
چکیده
منابع مشابه
Etiology and Evaluation of Sperm Chromatin Anomalies
Evidence suggests that human sperm chromatin anomalies adversely affect reproductive outcomes and infertile men possess substantially amount of sperm with chromatin anomalies than fertile men. Routine semen analysis evaluates parameters such as sperm motility and morphology, but does not examine the nuclear DNA integrity of spermatozoa. It has been suggested that altered nuclear chromatin struc...
متن کاملAssociation of sperm apoptosis and DNA ploidy with sperm chromatin quality in human spermatozoa.
OBJECTIVE To examine the relationship among sperm apoptosis, sperm chromatin status, and DNA ploidy in different sperm fractions. DESIGN Prospective study. SETTING Reproductive research center in a tertiary care hospital. INTERVENTION(S) Sperm prepared by density gradient were evaluated for sperm count, motility, apoptosis, and sperm chromatin assessment. MAIN OUTCOME MEASURE(S) Sperm c...
متن کاملAssociation of sperm protein 17 with A-kinase anchoring protein 3 in flagella
BACKGROUND Sperm protein 17 (Sp17) is a three-domain protein that contains: 1) a highly conserved N-terminal domain that is 45% identical to the human type II alpha regulatory subunit (RII alpha) of protein kinase A (PKA); 2) a central sulphated carbohydrate-binding domain; and 3) a C-terminal Ca++/calmodulin (CaM) binding domain. Although Sp17 was originally discovered and characterized in spe...
متن کاملP-19: Association of Poor Chromatin Remodeling with Cytosolic ROS and Mitochondrial ROS in Sperm of Infertile Men
Background: Cytoplasm and mitochondria are considered as the major origins of sperm ROS production. Sperm is prone to DNA damage by exposure to ROS or due impaired chromatin remodeling or low DNA protamination. Therefore, the aim of this study was to see if there is any association between impaired chromatin packaging and origin of ROS production. Materials and Methods: Cytosolic ROS, mitochond...
متن کاملThe structural organization of sperm chromatin.
The packaging of the male haploid genome within the differentiating spermatid nucleus is facilitated by small basic nuclear proteins called protamines. Although the majority of the DNA in human sperm chromatin is bound by these proteins, a small percentage retains a nucleosomal-like component. These histone-enriched regions may possess enhanced nuclease sensitivity and have been postulated to d...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Reproduction
سال: 1982
ISSN: 1470-1626,1741-7899
DOI: 10.1530/jrf.0.0660389